It's arguably the best crop in the game to use Deluxe Speed-Gro (DSG) on since it has a one-month maturation time (plant on 1st, harvest on 1st, not 28th) that you can shorten by 6 days. You can get 20 DSG as a reward for the donating to the Spring Crops Bundle at the Community Center. Or you can buy it or craft it later.
It's the long-term main high-dollar outdoor crop partly because it grows Spring, Summer, and Fall. Here's a spreadsheet that shows the reward of planting it on Spring 1 (Year 2+). You want to spend Year 1 building up your supply.
It's arguably the best Greenhouse crop long term, all things considered. See this comparison to make your own conclusion.
Plant ancient seeds outdoors through Summer 28 (or Fall 6 with DSG) unless you foresee available Greenhouse spaces less than 4 weeks in the future. See this analysis.
Plant ancient seeds in the Greenhouse with DSG until you have as many there as you want. Then make enough seeds for your next Spring 1 before you make or sell any Wine. Live on Pale Ale and Starfruit Wine income until you have all the Ancient Fruit seeds you want.